Should I select the new Power Delivery version of the IC for my new project?

The PD versions of the FT232H/FT2232H/FT4232H offer all the same data features whilst having much more flexibility in the power supply. Therefore, if your device requires more than 5V at 500mA to be supplied over USB, or if your device currently has its own power supply of up to 20V at 3A which you want to eliminate, you could consider the PD version.