How can you configure USB to UART chip to allow this to work in a special baud rate?

FTDI provide both D2XX and VCP drivers in Windows OS. With the D2XX driver, the user is only required to fill in the baud rate in the second parameter when they call FT_SetBaudRate API. With the VCP driver however, the user will be required to modify the ftdiport.inf file for the special baud rate. Application Note 120 – Aliasing VCP Baud Rates describes how to calculate the divisor for a non-standard baud rate.